Appearance( 25ºC) | white flakes |
Active Matter(%) | 50±5 |
PH Value (1% aqueous solution) | 7±1.5 |
Free Amine Content(%) | ≤0.50 |
Solid Content(%) | ≥50.0 |
Availability: | |
---|---|
Product name | 5-Azacytidine |
Other name | 4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazine-2(1H)-one |
Specification | EP/USP |
CAS | 320-67-2 |
Package | 25kg net per drum. |
Stock | Fresh stock; good price; samples available |
Molecular Structure | |
Molecular Formula | C8H12N4O5 |
Molecular Weight | 244.21 |
Introduction
Azacitidine (INN; trade name Vidaza) is a chemical analog of cytidine, a nucleoside in DNA and RNA. Azacitidine and its deoxy derivative, decitabine (also known as 5-aza-2′deoxycytidine), are used in the treatment of myelodysplastic syndrome. Both drugs were first synthesized in Czechoslovakia as potential chemotherapeutic agents for cancer.
For the treatment of the following subtypes of myeloplastic syndrome: Refractory anemia (RA), RARS (with neutropenia or thrombocytopenia or the need for blood transfusion), refractory anemia with protocytosis (RAEB), refractory anemia with protocytosis transformation (RAEB-T) And chronic granulomonocyte leukemia (CMMoL).